Zend certified PHP/Magento developer

Old .iso game says “This app can’t run on your PC” when i try to run the SETUP.EXE – Windows 10

I’m trying to run a childhood game i used to play all the time. I found an .iso file to the game and i have gotten it mounted as a drive and when i click the “SETUP.EXE” file it says “This app can’t run on your PC – To find a version for your PC, check with the software publisher”

Is there anyway to fix this problem or do i have to get a physical copy? I’m on a Windows 10 64bit system.