Is Local Group Policy more “resilient” than Registry?

The existing questions on Local Group Policy vs Registry (for example, this one) don’t seem to cover the following aspect:

In a non-enterprise context (i.e. it’s just me and my Windows 10 Pro), does it make any practical difference through which of the two to apply a change?

For me, an important practical difference would be if (for example) changes made via Local Group Policy were harder to undo, be it by the next Windows update or by some malicious software (that may or may not run elevated).